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Alzheimer's Disease

News, opinions and meeting coverage in geriatrics.

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Proteins Predict Signs of Alzheimer's Disease

Subclinical health indicators tied to markers of Alzheimer's and neurodegeneration

A computer rendering of the brain with the hippocampus highlighted.

Hippocampal Atrophy Might Not Signal Alzheimer's Disease

Measuring tau and hippocampus in addition to amyloid may improve Alzheimer's diagnosis

A computer rendering of amyloid beta peptide.

Gantenerumab Failed to Slow Cognitive Decline in Early Alzheimer's

Amyloid plaque levels went down, but not enough for clinical benefit

A photo of foods associated with the MIND diet.

MIND Diet in Midlife Tied to Higher Subcortical Brain Region Volumes

Relationships appear to hold regardless of Alzheimer's genes

A computer rendering of amyloid plaques collecting between neurons

Subcutaneous Alzheimer's Drug May Be on the Horizon

Investigational version of lecanemab shows promise, but questions about safety persist

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Dianne Feinstein Dies; Prison for Alzheimer's Fraudsters; Kaiser Strike Looming

Health news and commentary from around the Web gathered by 口袋女优 staff

A photo of a senior man receiving chemotherapy in an infusion clinic.

Experts Warn on Mixing New Alzheimer's Drug and Antidepressants

Patients starting SSRIs and lecanemab may warrant close monitoring

A computer rendering of amyloid plaques on a nerve cell.

Few Early Alzheimer's Patients Qualify for Lecanemab

Inclusion and exclusion criteria whittle down pool of eligible treatment candidates

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Quest's Alzheimer's Blood Test Has Experts Concerned

"Patients will have a difficult time knowing what the results mean"

A photo of a female healthcare worker holding her senior male patient鈥檚 hand.

CMS Announces New Dementia Care Model for Medicare Patients

Aims to provide more coordinated, ongoing care

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Alzheimer's Blood Tests May Improve Primary Care Diagnoses

Without biomarkers, primary care doctors correctly identified Alzheimer's in about 55% of cases

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Study of 1.6 Million Veterans Links Neighborhood and Dementia Risk

Despite equal access to care, health inequalities persisted in disadvantaged areas

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

This Common Device Can Slow Cognitive Decline, Trial Shows

Hearing loss is more than a marker for dementia risk, it appears

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Donanemab Slows Progression in Early Alzheimer's

Safety issues linger, as details of three deaths emerge

AAIC over a photo of the RAI convention center in Amsterdam, Netherlands.

Low Amyloid Burden Bodes Well for Future Dementia Risk

A ray of hope amidst disappointing results from A4 trial

A photo of the vial and packaging of Leqembi.

Registry Enrollment for Alzheimer's Drug Coverage Won't Help Much

A minimalist policy for a minimalist treatment

FDA APPROVED lecanemab (Leqembi) over a computer rendering of amyloid plaque on nerve cells.

Alzheimer's Drug Wins Full FDA Approval

Decision expands lecanemab's Medicare coverage

A photo of a senior man taking a cognitive test.

Without Early Detection, Fighting Dementia Is an Uphill Battle

A brief assessment in primary care can help identify patients most at risk

A photo of the vials and packaging Leqembi for injection.

Our Health Systems Aren't Ready for the Full Approval of Lecanemab

Screening, administration, and eligibility concerns remain

FDA ADCOMM lecanemab over a computer rendering of an antibody bound to an amyloid beta peptide.

Alzheimer's Drug Clears Major Hurdle Toward Full Approval

But risks associated with anti-amyloid agent lecanemab still loom

A photo of a mature man checking his blood sugar levels with a glucose meter.

Study Suggests Increase in Brain Aging in Those With Type 1 Diabetes

But this didn't seem to translate into Alzheimer's disease-related neurodegeneration

An illustration of a physician holding a patient's hand with the text The Doctor's Art - A podcast on Meaning in Medicine

Navigating My Father's Alzheimer's as a Doctor

Sandeep Jauhar, MD, PhD, on his career and wrestling with his father's dementia

A photo composite of a pipette hovering over brain MRI image in the bottom of a well tray.

Alzheimer's Progression Delayed by Rare Genetic Variant

Finding challenges previous assumptions about disease

FDA APPROVED brexpiprazole (Rexulti) over a photo of a agitated-looking senior woman.

FDA OKs First Drug for Agitation in Alzheimer's Dementia

Boxed warning on increased mortality risk in elderly patients remains for brexpiprazole

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AI Offers Hope for Those With Alzheimer's Disease

How tech can help make a better future for patients

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Alzheimer's Proteins Reduced by Sleep Drug

Both amyloid and tau levels fell in early trial

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Test Predicts Transition From Normal to Impaired Cognition

Sensitive, simple test detects subtle deficit at its earliest stage

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RF Ablation or Drugs for Afib: Choice May Matter for Cognitive Outcomes

New study suggests one does a better job of protecting the brain

FDA ADCOMM brexpiprazole (Rexulti) over a photo of an agitated senior woman rising her index finger.

FDA Advisors Endorse Rexulti for Agitation in Alzheimer's Dementia

Increased mortality risk seen but benefits may outweigh this, panelists say

FDA ADCOMM brexpiprazole (Rexulti) over a photo of an agitated senior woman rising her index finger.

Rexulti Works for Agitation in Alzheimer's, Despite Risks, Says FDA Staff

Increased mortality risk consistent with other antipsychotics in elderly dementia patients

A computer rendering of of amyloid plaques affecting neurons and neurofibrillary tangles inside neurons

Brains Shrink With Anti-Amyloid Alzheimer's Drugs

Treatments accelerate brain atrophy, but reasons why remain a mystery

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Autopsies Show Relationship Between Alzheimer's Pathology and Diet in Older Adults

Green leafy vegetable intake inversely correlated with pathology in postmortem brain tissue

A photo of a dissected brain affected by Alzheimer's disease.

We May Be Better at Fending Off Dementia, Autopsies Suggest

Neurodegeneration pathologies look similar across birth epochs as dementia incidence declines

A photo of a young physician talking to his senior male patient in his office.

There's No 'Recipe' to Reduce Dementia Risk -- Yet

Until more evidence emerges, here's how to discuss it with patients

A computer rendering of amyloid plaques on a neuron.

Blood Test Predicts Which People With Amyloid Are Likely to Decline Cognitively

Plasma p-tau217 outperformed other preclinical Alzheimer's measures

A computer rendering of amyloid plaques forming on a motor neuron.

Their Alzheimer's Disease Didn't Worsen. Why?

Case reports find one healthy habit in common

A computer rendering of viral encephalitis

Viruses Tied to Subsequent Dementia, Other Neurodegenerative Diseases

Viral encephalitis and Alzheimer's disease showed strongest links

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Memory Decline Tied to Lifestyle Factors

Healthy lifestyle slowed memory loss, even in APOE4 carriers

A microscope image of glial fibrillary acid protein astrocytes

Alzheimer's Disease Detected in Blood a Decade Before Clinical Symptoms

GFAP levels change before tau, neurodegeneration biomarkers

FDA APPROVED Lecanemab-irmb (Leqembi) over a computer rendering of amyloid plaques forming between neurons

Alzheimer's Drug Lecanemab Wins FDA Approval

Anti-amyloid showed modest benefit in phase III trial, but was linked to adverse events

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