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Peptic Ulcer Disease

News, opinions and meeting coverage in gastroenterology.

FDA Issues Warning on Acid Reflux Drugs

The FDA warned today that use of proton pump inhibitors -- including popular brands such as Nexium, Prilosec, and Prevacid -- may increase the risk of Clostridium difficile-associated diarrhea.

'Upset Stomach' Feels Better After Killing H. pylori

Eradicating Helicobacter pylori with antibiotics provided significant benefits to primary care patients with functional dyspepsia, according to results of a randomized trial.

Consumer Group Urges Boxed Warning for PPIs

Citing research showing that withdrawal of proton pump inhibitors (PPIs) leads to severe rebound acid secretion -- potentially leaving patients permanently dependent on the drugs -- the consumer group Public Citizen has told the FDA that it should require black-box warnings with the drugs.

Once-Chronic Peptic Ulcers Now Curable

Over the past 25 years, peptic ulcer disease went from a costly, chronic condition to one that can be eliminated with little chance of recurrence. But the road from point A to point B was not an easy one.

AHA: FDA Drops Clopidogrel Bomb at AHA

ORLANDO -- The FDA has issued a public health advisory warning patients and physicians that concommitant use of clopidogrel (Plavix) and omeprazole (Prilosec and Prilosec OTC) blunts the antiplatelet effect of clopidogrel, so the combination should be avoided.

Short-Term Use of High-Dose Ibuprofen Linked to GI Bleeding

HAMILTON, Ontario - Taking high doses of Advil or Motrin (ibuprofen) even for a few days can significantly increase the risk of gastrointestinal bleeding, researchers reported today.